Titin Illustrations

These illustrations were created for a review paper on the protein Titin. Titin is a protein found in the sarcomeres of cardiac muscle. Mutations in the gene sequence that codes for it can lead to shortened or misformed proteins that don’t function as effectively during muscle contraction. This can lead heart diseases such as dilated cardiomyopathy (DCM).

The three illustrations were created to illustrate:
– the structure and function of Titin
– a timeline of animal models used in its study
– the locations of other genes associated with dilated cardiomyopathy (DCM) not found in sarcomeres

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