
CRISPR-Cas Gene Editing: Biology, Technology and Ethics
2018
Jennifer Doudna
Summary of the science
The genome can be edited using proteins taken from bacteria. This protein is known as the Cas9 protein and when given a guide molecule, it can find DNA that contains the same sequence and cuts in, resulting in a gap. DNA molecules in the surrounding environment are then used to repair that gap. This technology therefore represents an accurate method of changing the genetic sequence of individuals and is a massive breakthrough in biochemistry. Jennifer Doudna developed this technology and her lab study how this technology may be used for other purposes.
About the research
Jennifer Doudna is a Nobel-prize winning scientist who has been credited with development of CRISPR-Cas gene editing, along with fellow researcher Emmanuelle Charpentier. Her lab's research continues to develop this technology, studying novel applications for the CRISPR-Cas system.
About the illustration