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A solid state conceptualization of information transfer from gene to message to protein
2017
Steven McKnight
Summary of the science
Genetic information moves from the nucleus in the centre of the cell to different parts of the cell for protein production. They propose that this information transfer is guided by temporary structures formed by specific protein segments. These protein segments are commonly found with proteins that control gene expression and RNA production, but they are also involved other cellular structures and processes. The researchers suggest that these structures, which are weakly assembled and easily disassembled, play a crucial role in accurately relaying genetic information within the cell, ensuring high fidelity in the process.
About the research
McKnight and his colleagues aim to understand the intricate process of genetic information flow from the nucleus to various sites in the cytoplasm, where proteins are made. They investigate the role of transient structures formed by small loose protein segments in guiding this information transfer. These protein structures are primarily associated with regulatory proteins, that control gene expression. However, they are also involved in other cellular processes, as evident by their presence near nuclear pores and points of intermediate filament assembly.
About the illustration