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self organisation in cells

Cells have have a remarkable ability to arrange their components into systems as an early stage of their development, aligning and connecting organelles with related responsibilities and functions.

To do this, cells in developing tissues organise themselves into complex structures based on a variety of signalling mechanisms. Some of these are concentration gradients of signalling factors that promote global polarity within tissue organisation. Others are intercellular signals that cells use to dictate to their neighbours how they should develop or migrate to form complex structures.