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Centriole assembly

Centrioles are cylindrical organelles made up of nine microtubules. They are essential to the formation of flagella, cilia and centrosomes.

Discovered following the invention of the electron microscope, centrioles have been described as cylinders made up of nine microtubules. Centrioles are poorly understood; however using fluorescent microscopy Pierre Gonczy has analysed the centriole assembly in C. elegans embryos. The study found that 3 pericentriolar material proteins are involved in the process of centriole assembly: SPD-5, the kinase aurora-A, and gamma-tubulin. The study also found that increasing gamma-tubulin concentration around the parent centriole led to development of the daughter structure.

This image was made in response to research by Pierre Gonczy